Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753847 | 0.86 | CA2 (0.67) | CA2CA1ALDH1A1MAPTCES2 | |
| SCHEMBL163209 | 0.82 | ALDH1A1 (0.72) | CA2CA1ALDH1A1MAPTGSK3B | |
| SCHEMBL31331813 | 0.81 | ALDH1A1 (0.67) | CA2CA1ALDH1A1MAPTCES2 | |
| SCHEMBL1229041 | 0.80 | CA2 (0.59) | CA2CA1ALDH1A1MAPTGSK3B | |
| SCHEMBL7383499 | 0.79 | CA1 (0.44) | CA2CA1ALDH1A1MAPTGSK3B | |
| Formaldehyde SCHEMBL27504509 | 0.78 | ALDH1A1 (0.68) | CA2CA1ALDH1A1MAPTGSK3B | |
| SCHEMBL6413833 | 0.78 | CES2 (0.65) | CA2CA1ALDH1A1MAPTCES2 | |
| SCHEMBL28991338 | 0.78 | CA1 (0.52) | CA2CA1ALDH1A1MAPTGSK3B | |
| SCHEMBL9365484 | 0.78 | CA1 (0.57) | CA2CA1ALDH1A1MAPTCES2 | |
| SCHEMBL9476052 | 0.77 | CYP11B1 (0.51) | CA2CA1ALDH1A1MAPTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065384-A1 | FLUORESCENT MRI PROBE | THE UNIVERSITY OF TOKYO (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120065384-A1 | FLUORESCENT MRI PROBE | THE UNIVERSITY OF TOKYO (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065384-A1 | FLUORESCENT MRI PROBE | GLRA1, GLRA3, GDI1 | CA2 213/4885CA1 18/4885ALDH1A1 3011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.