Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370567 | 0.85 | CNR2 (0.45) | FAAHLMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL4423581 | 0.75 | CNR1 (0.46) | FAAHNPC1RAB9AEPHX1MEN1 | |
| SCHEMBL4368598 | 0.74 | CNR2 (0.42) | CNR1CNR2 | |
| SCHEMBL3919199 | 0.73 | CNR1 (0.55) | FAAHLMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL3916843 | 0.73 | CNR1 (0.53) | FAAHLMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL4372987 | 0.72 | CNR1 (0.39) | FAAHHPGDCNR1CNR2 | |
| SCHEMBL4375089 | 0.70 | CNR1 (0.39) | FAAHCNR1 | |
| SCHEMBL3921317 | 0.70 | CNR2 (0.46) | FAAHLMNAHPGDSMN1; SMN2NPC1 | |
| SCHEMBL4424973 | 0.69 | MEN1 (0.46) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL4426908 | 0.69 | MEN1 (0.46) | LMNANPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |