SCHEMBL4371691

SCHEMBL4371691

O=C1C=CC(=O)N1c1ccc(S(=O)(=O)Cl)cc1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 16/20 0.62
FAAH O00519 6/20 0.62
HSP90AA1 P07900 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
BCHE P06276 1/20 0.52
PKM P14618 1/20 0.52
MAPK1 P28482 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
DDAH1 O94760 1/20 0.47
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
CCR6 P51684 1/20 0.46
CACNA1B Q00975 1/20 0.46
APBA1 Q02410 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331305 0.83 MGLL (0.68) MGLLFAAHHSP90AA1TDP1BCHE
SCHEMBL9718403 0.83 MGLL (0.68) MGLLFAAHHSP90AA1TDP1BCHE
SCHEMBL1632277 0.79 CA1 (0.63) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL28752490 0.79 MGLL (0.62) MGLLFAAHHSP90AA1TDP1BCHE
SCHEMBL1830817 0.79 MGLL (0.62) MGLLFAAHHSP90AA1TDP1BCHE
SCHEMBL32665177 0.79 MGLL (0.62) MGLLFAAHHSP90AA1TDP1BCHE
SCHEMBL95324 0.79 MGLL (1.00) MGLLFAAHHSP90AA1TDP1BCHE
SCHEMBL11384686 0.79 MGLL (0.56) MGLLFAAHHSP90AA1TDP1BCHE
SCHEMBL11388703 0.79 MGLL (0.56) MGLLFAAHHSP90AA1TDP1BCHE
SCHEMBL11594889 0.78 MGLL (0.60) MGLLFAAHHSP90AA1TDP1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651902-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651901-A1 CYCLING LYSOSOMAL TARGETING ANTIBODY CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
WO-2025035040-A1 LYSOSOMAL TARGETING BIFUNCTIONAL MOLECULES FOR DEGRADATION OF MUSCLE-SPECIFIC KINASE AUTOANTIBODIES LYCIA THERAPEUTICS, INC. (US) 2025-02-13 WO disclosed
WO-2024155747-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed
US-20090162290-A1 METHOD FOR THE SYNTHESIS OF PENTA-PENDANT ENANTIOMER-PURE CHELATORS AND PROCESS FOR THERAPEUTICALLY ACTIVE BIOCONJUGATES PREPARATION BY A COVALENT BINDING THEREOF THERAPHARM GMBH 2009-06-25 US disclosed
EP-1942949-A1 METHOD FOR THE SYNTHESIS OF PENTAPENDANT ENANTIOMER-PURE CHELATORS AND PROCESS FOR THERAPEUTICALLY ACTIVE BIO-CONJUGATES PREPARATION BY A COVALENT BINDING OF THEREOF Therapharm GmbH (CH) 2008-07-16 EP disclosed
WO-2007028639-A1 METHOD FOR THE SYNTHESIS OF PENTAPENDANT ENANTIOMER-PURE CHELATORS AND PROCESS FOR THERAPEUTICALLY ACTIVE BIO-CONJUGATES PREPARATION BY A COVALENT BINDING OF THEREOF THERAPHARM GMBH (CH) 2007-03-15 WO disclosed
EP-0025015-A2 Process for glueing a substrate coated with a zinciferous organic material CIBA-GEIGY AG (CH) 1981-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090162290-A1 METHOD FOR THE SYNTHESIS OF PENTA-PENDANT ENANTIOMER-PURE CHELATORS AND PROCESS FOR THERAPEUTICALLY ACTIVE BIOCONJUGATES PREPARATION BY A COVALENT BINDING THEREOF C5, C3AR1, SPR MGLL 4807/4885FAAH 4005/4885HSP90AA1 4337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.