SCHEMBL9718403

SCHEMBL9718403

O=C1C=CC(=O)N1c1ccc(S(=O)(=O)c2ccc(N3C(=O)C=CC3=O)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 16/20 0.68
FAAH O00519 6/20 0.68
HSP90AA1 P07900 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
PKM P14618 1/20 0.56
MAPK1 P28482 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
CCR6 P51684 1/20 0.53
CACNA1B Q00975 1/20 0.53
APBA1 Q02410 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53
BCHE P06276 1/20 0.50
DDAH1 O94760 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331305 1.00 MGLL (0.68) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL24119970 0.92 MGLL (0.63) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL27043314 0.89 MGLL (0.66) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL332770 0.89 MGLL (0.66) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL27043316 0.84 MGLL (0.60) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL8396902 0.83 MGLL (0.49) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL1830817 0.83 MGLL (0.62) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL32665177 0.83 MGLL (0.62) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL28752490 0.83 MGLL (0.62) MGLLFAAHHSP90AA1TDP1PKM
SCHEMBL1632277 0.83 CA1 (0.63) MGLLFAAHHSP90AA1TDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0510477-A1 Composition of polyarylene sulphides, dolomite and maleimides BAYER AG (DE) 1992-10-28 EP disclosed
EP-0443125-A1 Blends of polyarylene sulphides, metal salts, glass fibres and maleimides BAYER AG (DE) 1991-08-28 EP disclosed
EP-0396935-A2 Blends of polyarylenesulfides, glassfibres and maleimides BAYER AG (DE) 1990-11-14 EP disclosed