Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | TSHR | P16473 | 9/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896572 | 0.87 | CYP3A4 (0.50) | CYP3A4ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL4905609 | 0.85 | ALDH1A1 (0.69) | CYP3A4ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL1897234 | 0.85 | CYP3A4 (0.49) | CYP3A4ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL29030397 | 0.83 | CYP3A4 (0.53) | CYP3A4ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL1397837 | 0.83 | TSHR (0.71) | CYP3A4ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL4894269 | 0.81 | TSHR (0.71) | CYP3A4ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL4906053 | 0.81 | TSHR (0.49) | CYP3A4ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL1900819 | 0.81 | TSHR (0.57) | CYP3A4ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL4905671 | 0.81 | SCN1A (0.47) | CYP3A4ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL5064752 | 0.81 | TSHR (0.53) | CYP3A4ALDH1A1TSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383470-B1 | HAIR TREATMENT COMPOSITIONS | UNILEVER PLC (GB) | 2009-06-17 | — | — | EP | disclosed |
| EP-1383860-B1 | FABRIC CARE COMPOSITIONS | UNILEVER PLC (GB) | 2005-10-12 | — | — | EP | disclosed |
| US-6767883-B2 | Fabric care compositions | UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. | 2004-07-27 | — | — | US | disclosed |
| US-6696051-B2 | CONTAINING CORE PARTICLES HAVING A D3,2 AVERAGE PARTICLE SIZE OF 10-700 NM, AND COATED WITH COVALENTLY BONDED SILICONE POLYMER | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-02-24 | — | — | US | disclosed |
| EP-1383468-A2 | HAIR TREATMENT COMPOSITIONS | UNILEVER PLC (GB) | 2004-01-28 | — | — | EP | disclosed |
| EP-1383860-A1 | FABRIC CARE COMPOSITIONS | Unilever Plc (GB) | 2004-01-28 | — | — | EP | disclosed |
| EP-1383470-A2 | HAIR TREATMENT COMPOSITIONS | UNILEVER PLC (GB) | 2004-01-28 | — | — | EP | disclosed |
| US-20030095943-A1 | Hair treatment compositions | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-05-22 | — | — | US | disclosed |
| US-20020192367-A1 | Fabric care compositions | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2002-12-19 | — | — | US | disclosed |
| WO-2002087522-A2 | HAIR TREATMENT COMPOSITIONS | UNILEVER PLC (GB) | 2002-11-07 | — | — | WO | disclosed |
| US-6071987-A | FORMS AN ELASTOMER HAVING EXCELLENT MECHANICAL PROPERTIES UPON THE EVAPORATION OF THE VOLATILE COMPONENTS INCLUDING WATER BY HEATING | TOSHIBA SILICONE CO., LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| US-5916687-A | Film-formable emulsion type silicone composition for air bag and air bag | TOSHIBA SILICONE CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |
| EP-0822219-A2 | Film-formable emulsion type silicone composition for air bag and air bag | TOSHIBA SILICONE CO., LTD. (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0822232-A2 | Silicone emulsion composition and process for producing silicone powder therefrom | TOSHIBA SILICONE CO., LTD. (JP) | 1998-02-04 | — | — | EP | disclosed |
| EP-0433727-B1 | Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion | TOSHIBA SILICONE (JP) | 1995-08-02 | — | — | EP | disclosed |
| EP-0433906-B1 | Thermoplastic resin and process for producing the same | TOSHIBA SILICONE (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5218014-A | Graft polymer formed by graft polymerization of vinyl monomer onto colloidal silica core silicone shell particles | TOSHIBA SILICONE CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| US-5188899-A | SILICA-CORE SILICONE-SHELL PARTICLES, EMULSION CONTAINING THE SAME DISPERSED THEREIN, AND PROCESS FOR PRODUCING THE EMULSION | TOSHIBA SILICONE CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0433906-A2 | Thermoplastic resin and process for producing the same | TOSHIBA SILICONE CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |
| EP-0433727-A1 | Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion | TOSHIBA SILICONE CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030095943-A1 | Hair treatment compositions | SPTLC3, HACD3, C18orf63 | CYP3A4 2556/4885ALDH1A1 379/4885TSHR 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.