Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1897807 | 0.87 | ALDH1A1 (0.46) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL1900290 | 0.86 | ALDH1A1 (0.49) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL4903411 | 0.85 | ALDH1A1 (0.70) | TSHRALDH1A1CYP3A4HTTTDP1 | |
| SCHEMBL29754649 | 0.84 | TSHR (0.67) | TSHRALDH1A1CYP3A4HTTTDP1 | |
| SCHEMBL204946 | 0.84 | TSHR (0.67) | TSHRALDH1A1CYP3A4HTTTDP1 | |
| SCHEMBL4905609 | 0.83 | ALDH1A1 (0.69) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL29030384 | 0.82 | ALDH1A1 (0.56) | TSHRALDH1A1CYP3A4TP53HSD17B10 | |
| SCHEMBL1896572 | 0.81 | CYP3A4 (0.50) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL4371870 | 0.81 | CYP3A4 (0.50) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 | |
| SCHEMBL1397837 | 0.81 | TSHR (0.71) | TSHRALDH1A1CYP3A4TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812790-B | Organopolysiloxane graft polymers | 花王株式会社 | 2019-04-12 | — | — | CN | disclosed |
| EP-2927253-B1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORP (JP) | 2018-09-12 | — | — | EP | disclosed |
| US-9351920-B2 | Organopolysiloxane graft polymer | KAO CORPORATION (JP) | 2016-05-31 | — | — | US | disclosed |
| US-20150297498-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORPORATION (JP) | 2015-10-22 | — | — | US | disclosed |
| EP-2927253-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | Kao Corporation (JP) | 2015-10-07 | — | — | EP | disclosed |
| CN-104812790-A | Organopolysiloxane graft polymer | KAO CORP | 2015-07-29 | — | — | CN | disclosed |
| US-20080003288-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-7204997-B2 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2007-04-17 | — | — | US | disclosed |
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| US-20030152623-A1 | Responsive microgel and methods related thereto | SUPRATEK PHARMA INC. (CA) | 2003-08-14 | — | — | US | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| EP-0910351-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0907666-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. Searle & Co. (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| WO-1997049387-A1 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297498-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | IDUA, PIGS, GMNN | TSHR 2848/4885ALDH1A1 2410/4885CYP3A4 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.