SCHEMBL4371889

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4376434	0.89	NPC1 (0.36)	CYP2C9CYP2C19HTR2BMAPK14SLC6A2
	SCHEMBL4372482	0.87	SLC6A2 (0.42)	SLC6A2SLC6A4OPRM1OPRD1OPRK1
	SCHEMBL4374674	0.87	ALDH1A1 (0.38)	CYP2C9CYP2C19HTR2BMAPK14SLC6A2
	SCHEMBL4371073	0.84	SLC6A2 (0.38)	SLC6A2SLC6A4OPRM1OPRD1OPRK1
	SCHEMBL4371916	0.81	EPHX2 (0.39)	SLC6A2SLC6A4OPRK1MEN1KMT2A
	SCHEMBL4372403	0.81	AGER (0.39)	SLC6A2SLC6A4OPRM1OPRD1OPRK1
	SCHEMBL4372256	0.79	OPRK1 (0.41)	SLC6A2SLC6A4OPRM1OPRD1OPRK1
	SCHEMBL4375515	0.78	OPRM1 (0.41)	SLC6A2SLC6A4OPRM1OPRD1OPRK1
	SCHEMBL4377337	0.78	SLC18A3 (0.40)	SLC6A2SLC6A4OPRM1OPRD1OPRK1
	SCHEMBL4372736	0.78	SLC6A2 (0.39)	CYP2C9CYP2C19HTR2BMAPK14SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.