Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9576852 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL26654550 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14243879 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL614488 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL27986975 | 0.94 | — | — | |
| Bicarbonate SCHEMBL6580035 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28193174 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1679609 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL10408290 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL7518275 | 0.94 | CA4 (0.50) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1561 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12630578-B2 | Methods for the production of calcium, magnesium, and zinc salts of sugar acids | DFI USA, LLC (US) | 2026-05-19 | — | — | US | claimed |
| EP-4418865-B1 | LIQUID COMPOSITION CONTAINING A COMBINATION OF VITAMINS A, D, E AND K IN A LIQUID MATRIX | LIPOID GMBH (DE) | 2025-12-10 | — | — | EP | claimed |
| US-20250228997-A1 | BONE REGENERATIVE AGENT AND METHOD OF USING SAME | JFE MINERAL COMPANY, LTD. (JP) | 2025-07-17 | — | — | US | claimed |
| US-20250170034-A1 | COMPOSITION FOR TOOTH WHITENING OR IMPROVING DENTIN HYPERSENSITIVITY COMPRISING POLYPHOSPHATE | LG H & H CO., LTD. (KR) | 2025-05-29 | — | — | US | claimed |
| CN-119925179-A | Composition for tooth whitening or improving dentin hypersensitivity comprising polyphosphate | 株式会社LG生活健康 | 2025-05-06 | — | — | CN | claimed |
| CN-119774741-A | Sewage purification equipment and purification method for preparing basic zinc carbonate | 福建冠鑫新材料有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-119632890-A | Berry composition for scalp care and preparation method and application thereof | 拉芳家化股份有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119564519-A | Toothpaste composition for inhibiting dental plaque and improving gingivitis, finished toothpaste and preparation method thereof | 马应龙大健康有限公司 | 2025-03-07 | — | — | CN | claimed |
| EP-4005636-B1 | BONE REGENERATIVE AGENT AND METHOD OF USING SAME | JFE MINERAL CO LTD (JP) | 2025-01-08 | — | — | EP | claimed |
| CN-119112749-A | Anti-aging repairing cosmetic composition, and preparation method and application thereof | 马应龙大健康有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-1353146-A | Process for preparing composite nano material and its application in modifying polyester | QILU CHEMICAL FIBER GROUP CO L (CN) | 2002-06-12 | — | — | CN | claimed |
| US-6107534-A | USING THE IMPROVED ZEOLITE CATALYST IN THE CONVERSION OF HYDROCARBONS, PREFERABLY NON-AROMATIC HYDROCARBONS, TO LOWER OLEFINS (SUCH AS ETHYLENE AND PROPYLENE) AND AROMATIC HYDROCARBONS (SUCH AS BENZENE, TOLUENE, AND XYLENE) | PHILLIPS PETROLEUM COMPANY (US) | 2000-08-22 | — | — | US | claimed |
| US-6084142-A | HYDROFINING TO FORM LOWER OLEFINS AND AROMATICS USING ZINC-INCORPORATED AND STEAM TREATED ZEOLITE ZSM-5; NONCOKING | PHILLIPS PETROLEUM COMPANY (US) | 2000-07-04 | — | — | US | claimed |
| US-6037294-A | ACID-TREATING ZEOLITE, ION-EXCHANGING WITH ZINC AND AT LEAST ONE GROUP 6B METAL, THEN STEAM TREATING | PHILLIPS PETROLEUM COMPANY (US) | 2000-03-14 | — | — | US | claimed |
| US-5981417-A | TREATING ZEOLITE WITH AN ACID TO FORM ACID-TREATED ZEOLITE, STEAM TREATING ABOVE ZEOLITE, IMPREGNATING BORON COMPONENT AND ZINC COMPONENT WITH STEAM AND ACID TREATED ZEOLITE, AND STEAM TREATING INCORPORATED ZEOLITE | PHILLIPS PETROLEUM COMPANY (US) | 1999-11-09 | — | — | US | claimed |
| US-5945371-A | ZINC AND MOLYBDENUM MIXED OXIDE HYDRODEALKYLATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1999-08-31 | — | — | US | claimed |
| US-5789642-A | HYDROREFINING CATALYSTS OF ALUMINA WITH MOLYBDENUM AND ZINC, REMOVAL OF EXCESS LIQUID AND DRYING AND ROASTING | PHILLIPS PETROLEUM COMPANY (US) | 1998-08-04 | — | — | US | claimed |
| US-4720380-A | Hydrogen-phosphide releasing compositions and processes for their production and use | DR. WERNER FREYBERG CHEMISCHE FEBRIK DELITIA NASCHF. (DE) | 1988-01-19 | — | — | US | claimed |
| EP-0109635-B1 | PROCESS FOR PURIFYING GASES CONTAINING CO AND/OR CO2 | BASF Aktiengesellschaft (DE) | 1986-03-19 | — | — | EP | claimed |
| US-4503032-A | ALUMINUM PHOSPHIDE, AMMONIA SOURCE, ZINC OR ZINC COMPOUND | DR. WERNER FREYBERG CHEMISCHE FABRIK DELITIA NACHF (DE) | 1985-03-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630578-B2 | Methods for the production of calcium, magnesium, and zinc salts of sugar acids | SLC5A6, SOD1, MGAM | CA4 85/4885CA1 64/4885FAHD1 1519/4885 |
| US-20250170034-A1 | COMPOSITION FOR TOOTH WHITENING OR IMPROVING DENTIN HYPERSENSITIVITY COMPRISING POLYPHOSPHATE | KCNN3, KCNN1, POLR1C | CA4 1497/4885CA1 1612/4885FAHD1 2344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.