SCHEMBL19320231

SCHEMBL19320231

CCCC(=O)CC(=O)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FAAH O00519 11/20 0.39
CES1 P23141 8/20 0.38
CES2 O00748 3/20 0.38
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HDAC3 O15379 3/20 0.34
HDAC1 Q13547 3/20 0.34
HDAC2 Q92769 3/20 0.34
HDAC8 Q9BY41 3/20 0.34
HDAC6 Q9UBN7 1/20 0.34
LIPA P38571 1/20 0.34
FFAR3 O14843 2/20 0.33
CTSD P07339 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4373902 0.86 FAAH (0.53) FAAHCES1CES2MEN1CYP1A2
SCHEMBL28687905 0.84 FAAH (0.55) FAAHCES1CES2MEN1CYP1A2
SCHEMBL7638938 0.82 TDP1 (0.41) FAAHCES1CES2MEN1CYP1A2
SCHEMBL6314290 0.82 FAAH (0.52) FAAHCES1CES2MEN1CYP1A2
SCHEMBL5323967 0.81 FAAH (0.44) FAAHCES1CES2MEN1CYP1A2
SCHEMBL23009369 0.81 FAAH (0.38) FAAHCES1CES2MEN1CYP1A2
SCHEMBL8562872 0.78 FAAH (0.39) FAAHCES1CES2MEN1CYP1A2
SCHEMBL18844136 0.76 FAAH (0.42) FAAHCES1CES2MEN1CYP1A2
SCHEMBL7640644 0.75 LIPA (0.39) MEN1KMT2AHDAC6LIPA
SCHEMBL4371316 0.75 FAAH (0.50) FAAHCES1CES2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170253623-A1 IRIDIUM COMPLEX PRODUCTION METHOD TANAKA KIKINZOKU KOGYO K.K. (JP) 2017-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170253623-A1 IRIDIUM COMPLEX PRODUCTION METHOD IPMK, TALDO1, BCKDK FAAH 3210/4885CES1 2112/4885CES2 3625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.