SCHEMBL4374133

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4378791	0.92	OPRM1 (0.41)	SLC6A2SLC6A4OPRM1CHRM2CHRM1
	SCHEMBL3241567	0.91	SLC6A2 (0.55)	SLC6A2SLC6A4OPRM1CHRM2CHRM1
	SCHEMBL4371972	0.91	SLC6A4 (0.41)	SLC6A2SLC6A4OPRM1CHRM2CHRM1
	SCHEMBL4372060	0.91	TRPA1 (0.44)	SLC6A2SLC6A4OPRM1CHRM2CHRM1
	SCHEMBL4371775	0.89	SLC6A4 (0.47)	SLC6A2SLC6A4OPRM1CHRM2CHRM1
	SCHEMBL4372443	0.89	SLC6A2 (0.39)	SLC6A2SLC6A4OPRM1CHRM2CHRM1
	SCHEMBL4370610	0.89	SLC6A4 (0.45)	SLC6A2SLC6A4OPRM1CHRM2CHRM1
	SCHEMBL4371850	0.89	OPRD1 (0.59)	SLC6A2SLC6A4OPRM1OPRD1OPRK1
	SCHEMBL4373199	0.88	LMNA (0.47)	SLC6A2SLC6A4OPRM1CHRM2CHRM1
	SCHEMBL4374260	0.88	SLC6A2 (0.44)	SLC6A2SLC6A4OPRM1CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.