Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432899 | 0.90 | CYP3A4 (0.47) | MAPTCYP3A4CYP2C9TDP1ALDH1A1 | |
| SCHEMBL8027004 | 0.85 | CYP3A4 (0.47) | MAPTGAACYP3A4CYP2C9ATM | |
| SCHEMBL16068737 | 0.81 | CYP3A4 (0.44) | MAPTGAACYP3A4CYP2C9TDP1 | |
| SCHEMBL13228091 | 0.80 | MAPT (0.42) | MAPTGAACYP3A4CYP2C9TDP1 | |
| SCHEMBL11022536 | 0.79 | CYP3A4 (0.46) | MAPTCYP3A4CYP2C9TDP1ALDH1A1 | |
| SCHEMBL9365929 | 0.78 | CYP3A4 (0.45) | MAPTCYP3A4CYP2C9ABCB1TDP1 | |
| SCHEMBL3900032 | 0.77 | KYAT1 (0.46) | MAPTGAACYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL3533537 | 0.77 | LMNA (0.47) | MAPTGAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL15918360 | 0.76 | CASP1 (0.71) | MAPTGAACYP3A4CYP2C9ATM | |
| SCHEMBL7933386 | 0.75 | CYP3A4 (0.43) | MAPTCYP3A4CYP2C9TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |