SCHEMBL4375389

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4377913	0.93	ALDH1A1 (0.59)	FKBP1AALDH1A1MAPTLMNASMN1; SMN2
	SCHEMBL4378642	0.86	L3MBTL1 (0.57)	ALDH1A1MAPTLMNAME2ME1
	SCHEMBL4378969	0.85	ME2 (0.53)	FKBP1AALDH1A1MAPTLMNASMN1; SMN2
	SCHEMBL2824010	0.85	MEN1 (0.72)	FKBP1AALDH1A1MAPTLMNASMN1; SMN2
	SCHEMBL4375437	0.85	KMT2A (0.72)	ALDH1A1LMNASMN1; SMN2GAAPOLB
	SCHEMBL4377632	0.82	MAPK1 (0.75)	FKBP1AALDH1A1MAPTSMN1; SMN2GAA
	SCHEMBL4377690	0.82	KMT2A (0.72)	ALDH1A1GAAPOLBKMT2AMEN1
	SCHEMBL4375445	0.81	HRH3 (0.60)	ALDH1A1MAPTSMN1; SMN2ME2ME1
	SCHEMBL10305162	0.80	FKBP1A (0.76)	FKBP1AALDH1A1MAPTLMNASMN1; SMN2
	SCHEMBL7369347	0.80	ALDH1A1 (0.55)	ALDH1A1MAPTLMNASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.