Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAT2A | P31153 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GOT1 | P17174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21223004 | 0.77 | MAPT (0.41) | MAPTKDM4EALDH1A1GAAP2RX7 | |
| SCHEMBL29505062 | 0.74 | MAT2A (0.42) | KDM4EALDH1A1P2RX7MAT2AKMT2A | |
| SCHEMBL14955141 | 0.74 | MAT2A (0.42) | KDM4EALDH1A1P2RX7MAT2AKMT2A | |
| SCHEMBL4371685 | 0.73 | NT5E (0.39) | KDM4EALDH1A1P2RX7MAT2ANT5E | |
| SCHEMBL7024893 | 0.73 | MAPT (0.41) | MAPTKDM4EALDH1A1GAARAB9A | |
| SCHEMBL24761059 | 0.72 | TAS2R14 (0.44) | MAPTKDM4EALDH1A1GAAP2RX7 | |
| SCHEMBL2634744 | 0.71 | NOTUM (0.42) | KDM4EALDH1A1MAT2ANT5EHSD17B10 | |
| SCHEMBL15284060 | 0.71 | NT5E (0.38) | KDM4EALDH1A1MAT2ANT5EHSD17B10 | |
| SCHEMBL15294527 | 0.69 | MAPT (0.38) | MAPTKDM4EALDH1A1GAAP2RX7 | |
| SCHEMBL404271 | 0.69 | KDM4E (0.41) | KDM4EGAALMNANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2831044-B1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | DOW AGROSCIENCES LLC (US) | 2020-11-11 | — | — | EP | disclosed |
| EP-2831044-B1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | DOW AGROSCIENCES LLC (US) | 2020-11-11 | — | — | EP | disclosed |
| CN-104321310-B | Process for preparing 3-substituted-6-trifluoromethylpyridines and process for using 6-trichloromethyl halopyridines | 陶氏益农公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-2831044-A1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | Dow AgroSciences LLC (US) | 2015-02-04 | — | — | EP | disclosed |
| CN-104321310-A | Process for preparing 3-substituted-6-trifluoromethylpyridines and process for using 6-trichloromethyl halopyridines | DOW AGROSCIENCES LLC | 2015-01-28 | — | — | CN | disclosed |
| US-8785650-B2 | Methods for preparing 3-substituted-6-trifluoromethyl pyridines and methods for using 6-trichloromethyl halogenated pyridines | DOW AGROSCIENCES, LLC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785650-B2 | Methods for preparing 3-substituted-6-trifluoromethyl pyridines and methods for using 6-trichloromethyl halogenated pyridines | DOW AGROSCIENCES, LLC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130261310-A1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | CORTEVA AGRISCIENCE LLC | 2013-10-03 | — | — | US | disclosed |
| US-20130261310-A1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | CORTEVA AGRISCIENCE LLC | 2013-10-03 | — | — | US | disclosed |
| WO-2013148338-A1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | DOW AGROSCIENCES LLC (US) | 2013-10-03 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261310-A1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | CYP4F3, CBR3, PRDX6 | MAPT 4755/4885KDM4E 1199/4885ALDH1A1 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.