SCHEMBL4375495

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4373099	0.92	HTR7 (0.53)	APPHTR7ADORA1ADORA2AADORA2B
	SCHEMBL4372829	0.89	HTR7 (0.58)	APPHTR7ADORA1ADORA2AADORA2B
	SCHEMBL4377382	0.85	HTR7 (0.56)	APPHTR7ADORA1ADORA2AADORA2B
	SCHEMBL4373322	0.84	HTR7 (0.50)	HTR7
	SCHEMBL4377313	0.83	HTR7 (0.47)	APPHTR7ADORA1ADORA2AADORA2B
	SCHEMBL4376850	0.80	APP (0.52)	APPHTR7ADORA1ADORA2AADORA2B
	SCHEMBL4377737	0.79	APP (0.47)	APPHTR7ADORA1ADORA2AADORA2B
	SCHEMBL4380401	0.78	HTR7 (0.50)	APPHTR7ADORA1ADORA2A
	SCHEMBL4376041	0.78	APP (0.49)	APPMYLKADORA1ADORA2AADORA2B
	SCHEMBL4374779	0.76	ADORA2A (0.50)	HTR7ADORA1ADORA2AADORA2BADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.