SCHEMBL4380401

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4373099	0.85	HTR7 (0.53)	HTR7HTR2CHRH3APPADORA2A
	SCHEMBL4377313	0.82	HTR7 (0.47)	HTR7OGAFGFR1APPMAPK8
	SCHEMBL4377382	0.81	HTR7 (0.56)	HTR7APPADORA2AADORA1
	SCHEMBL4374779	0.80	ADORA2A (0.50)	HTR7HTR2CADORA2AADORA1IGF1R
	SCHEMBL4375495	0.78	APP (0.46)	HTR7APPADORA2AADORA1
	SCHEMBL4372829	0.78	HTR7 (0.58)	HTR7HTR2CAPPADORA2AADORA1
	SCHEMBL4372215	0.78	AOC3 (0.44)	HTR7TAAR1
	SCHEMBL4377737	0.76	APP (0.47)	HTR7HTR2CCYP1A2CYP2C19APP
	SCHEMBL4380313	0.73	HTR7 (0.76)	HTR7HTR2CCYP1A2ALDH1A1CYP2C19
	SCHEMBL4373322	0.72	HTR7 (0.50)	HTR7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.