SCHEMBL4375741

SCHEMBL4375741

COc1ccnc(F)c1OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAK O14976 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
IDO1 P14902 1/20 0.37
TDO2 P48775 1/20 0.37
MAOA P21397 1/20 0.36
RUNX1 Q01196 1/20 0.36
NFE2L2 Q16236 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2C P18825 1/20 0.36
ADRA1D P25100 1/20 0.36
ADRA1A P35348 1/20 0.36
ADRA1B P35368 1/20 0.36
SYK P43405 1/20 0.35
BRD4 O60885 2/20 0.35
TRPA1 O75762 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4376433 0.84 HPGD (0.44) SMN1; SMN2SYKCYP1A2CYP2D6CYP2C19
SCHEMBL31189728 0.81 ENPP2 (0.32) GAKSMN1; SMN2IDO1TDO2RUNX1
SCHEMBL31284870 0.78 GAK (0.38) GAKSMN1; SMN2IDO1TDO2MAOA
SCHEMBL4074317 0.78 ALDH1A1 (0.36) TRPA1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4370260 0.77 TDP1 (0.37) GAKMAOACYP3A4
SCHEMBL16012069 0.77 CYP1A2 (0.34) TRPA1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4074314 0.77 CYP1A2 (0.34) TRPA1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15112982 0.77 MAOA (0.35) GAKSMN1; SMN2MAOARIPK2COQ8A
SCHEMBL30851753 0.77 HPGD (0.40) SMN1; SMN2TRPA1CYP1A2CYP3A4CYP2D6
SCHEMBL7849683 0.77 IKBKB (0.41) TRPA1CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114361590-B Electrolyte additive for lithium ion battery, electrolyte and lithium ion battery 松山湖材料实验室 2023-07-25 CN claimed
WO-2009103950-A1 FLUORINATED PYRIDIN-4-0NES BTG INTERNATIONAL LIMITED (GB) 2009-08-27 WO disclosed