Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | NOS1 | P29475 | 1/20 | 0.60 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | QPCT | Q16769 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13185078 | 0.90 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPSR1 | |
| SCHEMBL10290016 | 0.85 | KMT2A (0.68) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL687852 | 0.84 | KMT2A (0.67) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPSR1 | |
| SCHEMBL15075252 | 0.82 | KMT2A (1.00) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPSR1 | |
| SCHEMBL5760109 | 0.80 | HMOX1 (0.65) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL28774231 | 0.80 | KMT2A (0.95) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPSR1 | |
| SCHEMBL1927388 | 0.79 | KMT2A (0.71) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPSR1 | |
| SCHEMBL5759151 | 0.79 | HMOX1 (0.64) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPSR1 | |
| SCHEMBL18737490 | 0.79 | KMT2A (0.70) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPSR1 | |
| SCHEMBL4390068 | 0.79 | KMT2A (0.72) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |