Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 15/20 | 0.34 |
| ▸ | CCR1 | P32246 | 12/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987163 | 0.93 | CHRM2 (0.33) | MCHR1CCR3CCR1CHRM2CHRM1 | |
| SCHEMBL7994725 | 0.74 | L3MBTL1 (0.33) | — | |
| SCHEMBL4378229 | 0.72 | HRH4 (0.31) | — | |
| SCHEMBL4385043 | 0.72 | GLS (0.33) | — | |
| SCHEMBL4385039 | 0.72 | TRPV1 (0.36) | — | |
| SCHEMBL4382422 | 0.72 | TRPV1 (0.36) | — | |
| SCHEMBL8450696 | 0.72 | HDAC1 (0.40) | — | |
| SCHEMBL4376607 | 0.71 | SSTR4 (0.32) | — | |
| SCHEMBL3055301 | 0.71 | CNR1 (0.50) | — | |
| SCHEMBL13734799 | 0.71 | MAPT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | claimed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |