Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994725 | 0.90 | L3MBTL1 (0.33) | RAB9AGAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL17473831 | 0.87 | MMP9 (0.35) | MAPTRAB9AQPCTQPCTLALDH1A1 | |
| SCHEMBL21820172 | 0.87 | CNR1 (0.36) | QPCTQPCTLALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL4385039 | 0.87 | TRPV1 (0.36) | HPGDSMN1; SMN2KMT2A | |
| SCHEMBL4382422 | 0.87 | TRPV1 (0.36) | HPGDSMN1; SMN2KMT2A | |
| SCHEMBL17473828 | 0.86 | ST14 (0.36) | MAPTRAB9AHTTGAAQPCT | |
| Oxalic Acid SCHEMBL31530509 | 0.85 | HPGD (0.35) | MAPTHTTGAAHPGDSMN1; SMN2 | |
| SCHEMBL5508626 | 0.84 | NOTUM (0.38) | RAB9AQPCTQPCTLALDH1A1L3MBTL1 | |
| SCHEMBL514228 | 0.84 | QPCT (0.49) | MAPTHTTQPCTQPCTLHPGD | |
| SCHEMBL17473827 | 0.84 | CYP3A4 (0.41) | HPGDL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116546988-A | Prodrugs of 5α -hydroxy-6β - [2- (1H-imidazol-4-yl) ethylamino ] cholestan-3β -ol and pharmaceutical compositions for cancer treatment containing the same | 登德罗杰尼克斯公司 | 2023-08-04 | — | — | CN | claimed |
| CN-113396153-A | Amino acid salts of nicotinic acid mononucleotide and nicotinamide mononucleotide as anti-aging agents | 江普斯塔特生育有限公司 | 2021-09-14 | — | — | CN | claimed |
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | claimed |
| US-9511073-B2 | Aromatic amides and uses thereof | TAXIS PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | claimed |
| US-20140135332-A1 | AROMATIC AMIDES AND USES THEREOF | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2014-05-15 | — | — | US | claimed |
| EP-2699557-A1 | AROMATIC AMIDES AND USES THEREOF | Biota Scientific Management Pty Ltd (AU) | 2014-02-26 | — | — | EP | claimed |
| WO-2012142671-A1 | AROMATIC AMIDES AND USES THEREOF | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-10-26 | — | — | WO | claimed |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | THE SCRIPPS RESEARCH INSTITUTE | 2024-04-02 | — | — | US | disclosed |
| US-20230331737-A1 | MTORC1 MODULATORS AND USES THEREOF | AEOVIAN PHARMACEUTICALS, INC. | 2023-10-19 | — | — | US | disclosed |
| CN-116546988-A | Prodrugs of 5α -hydroxy-6β - [2- (1H-imidazol-4-yl) ethylamino ] cholestan-3β -ol and pharmaceutical compositions for cancer treatment containing the same | 登德罗杰尼克斯公司 | 2023-08-04 | — | — | CN | disclosed |
| US-20220204485-A1 | STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | THE SCRIPPS RESEARCH INSTITUTE | 2022-06-30 | — | — | US | disclosed |
| EP-3946604-A1 | BENZOPYRANE AND IMIDAZOLE DERIVATIVES USEFUL FOR THE STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | The Scripps Research Institute (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-113396153-A | Amino acid salts of nicotinic acid mononucleotide and nicotinamide mononucleotide as anti-aging agents | 江普斯塔特生育有限公司 | 2021-09-14 | — | — | CN | disclosed |
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | disclosed |
| US-20170079895-A1 | PEPTIDE NANOPARTICLES AND USES THEREFOR | ANTERIOS, INC. | 2017-03-23 | — | — | US | disclosed |
| US-9486409-B2 | Peptide nanoparticles and uses therefor | ANTERIOS, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| EP-2944637-A1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM Corporation (JP) | 2015-11-18 | — | — | EP | disclosed |
| US-20150322063-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2015-11-12 | — | — | US | disclosed |
| US-20150196490-A1 | NANOPARTICLE COMPOSITIONS | ANTERIOS, INC. | 2015-07-16 | — | — | US | disclosed |
| US-20140234382-A1 | PEPTIDE NANOPARTICLES AND USES THEREFOR | ANTERIOS, INC. (US) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331737-A1 | MTORC1 MODULATORS AND USES THEREOF | MTOR, RPTOR, RICTOR | MAPT 1500/4885RAB9A 462/4885HTT 232/4885 |
| US-20220204485-A1 | STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | TTR, MAP1LC3B, SAAL1 | MAPT 41/4885RAB9A 3384/4885HTT 414/4885 |
| US-20150196490-A1 | NANOPARTICLE COMPOSITIONS | KRT18, CUTA, HRAS | MAPT 406/4885RAB9A 285/4885HTT 736/4885 |
| US-20150322063-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | NPM1, NAP1L1, REN | MAPT 3508/4885RAB9A 505/4885HTT 1732/4885 |
| US-20170079895-A1 | PEPTIDE NANOPARTICLES AND USES THEREFOR | NGLY1, SPPL2B, TFIP11 | MAPT 3191/4885RAB9A 3510/4885HTT 1707/4885 |
| US-20140234382-A1 | PEPTIDE NANOPARTICLES AND USES THEREFOR | NGLY1, SPPL2B, TFIP11 | MAPT 3191/4885RAB9A 3510/4885HTT 1707/4885 |
| US-20140135332-A1 | AROMATIC AMIDES AND USES THEREOF | NAT1, ASNS, CYP2C9 | MAPT 2119/4885RAB9A 1391/4885HTT 3614/4885 |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | TTR, MAP1LC3B, SAAL1 | MAPT 41/4885RAB9A 3384/4885HTT 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.