Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.43 |
| ▸ | CBLB | Q13191 | 4/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376910 | 0.88 | SCN2A (0.52) | — | |
| SCHEMBL4375164 | 0.87 | SCN2A (0.40) | ACKR3 | |
| SCHEMBL2065546 | 0.71 | KDR (0.40) | CBLBKDRPDGFRB | |
| SCHEMBL2065544 | 0.71 | KDR (0.40) | CBLBKDRPDGFRB | |
| SCHEMBL1135876 | 0.70 | — | — | |
| SCHEMBL24775458 | 0.69 | RIPK1 (0.40) | TRPM8TRPV1 | |
| SCHEMBL21695727 | 0.65 | ACKR3 (0.55) | ACKR3KDR | |
| SCHEMBL21133250 | 0.64 | FADS1 (0.56) | CBLBCSF1RKDRUSP36PDGFRB | |
| SCHEMBL21348782 | 0.63 | CBLB (0.53) | ACKR3CBLB | |
| SCHEMBL15238443 | 0.63 | MEN1 (0.75) | CSF1RKDRUSP36 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285810-A1 | SELECTIVE LIGANDS FOR THE NEURONAL NICOTINIC RECEPTORS AND USES THEREOF | Abbott Laboratories (US) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009137308-A1 | SELECTIVE LIGANDS FOR THE NEURONAL NICOTINIC RECEPTORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-11-12 | — | — | WO | disclosed |