SCHEMBL4377986

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL649039	0.87	CKS1B (0.65)	GPR119CKS1BSKP1SKP2ALDH1A1
	SCHEMBL4417334	0.85	GPR119 (0.59)	GPR119CKS1BSKP1SKP2ALDH1A1
	SCHEMBL1908712	0.85	ALDH1A1 (0.53)	GPR119CKS1BSKP1SKP2ALDH1A1
	SCHEMBL359301	0.85	ALDH1A1 (0.53)	GPR119ALDH1A1DRD2LMNACA12
	SCHEMBL4371640	0.84	ALDH1A1 (0.54)	ALDH1A1DRD2LMNACA12CA1
	SCHEMBL4233864	0.82	ALDH1A1 (0.54)	ALDH1A1DRD2LMNACA12CA1
	SCHEMBL3156635	0.82	ALDH1A1 (0.54)	ALDH1A1DRD2LMNACA12CA1
	SCHEMBL239933	0.81	GPR119 (0.63)	GPR119CKS1BSKP1SKP2ALDH1A1
	SCHEMBL1908728	0.81	ALDH1A1 (0.51)	GPR119CKS1BSKP1SKP2ALDH1A1
	SCHEMBL1401964	0.81	GPR119 (0.58)	GPR119CKS1BSKP1SKP2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.