Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958027 | 0.84 | KCNA3 (0.46) | L3MBTL1MAPTHPGDALDH1A1KMT2A | |
| Amotosalen SCHEMBL29442584 | 0.79 | MAOA (0.44) | L3MBTL1MAPTHPGDALDH1A1KMT2A | |
| SCHEMBL1115728 | 0.79 | L3MBTL1 (0.44) | L3MBTL1MAPTHPGDALDH1A1KMT2A | |
| Amotosalen SCHEMBL599618 | 0.79 | MAOA (0.44) | L3MBTL1MAPTHPGDALDH1A1KMT2A | |
| Amotosalen SCHEMBL4197287 | 0.78 | MAOA (0.43) | L3MBTL1MAPTHPGDALDH1A1KMT2A | |
| SCHEMBL13078690 | 0.78 | MAOA (0.50) | L3MBTL1MAPTHPGDALDH1A1KMT2A | |
| SCHEMBL3359066 | 0.77 | MAOA (0.42) | L3MBTL1MAPTHPGDALDH1A1KMT2A | |
| SCHEMBL21585417 | 0.77 | MAOA (0.42) | L3MBTL1MAPTHPGDALDH1A1KMT2A | |
| SCHEMBL21585418 | 0.77 | MAOB (0.42) | L3MBTL1MAPTHPGDALDH1A1KMT2A | |
| Amotosalen SCHEMBL15229366 | 0.77 | MAOA (0.42) | L3MBTL1MAPTHPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1584622-B1 | Compounds for the photodecontamination of pathogens in blood | CERUS CORP (US) | 2009-11-11 | — | — | EP | disclosed |
| EP-1776952-A2 | Photodecontamination of pathogens in blood | Cerus Corporation (US) | 2007-04-25 | — | — | EP | disclosed |
| EP-0707476-B1 | COMPOUNDS FOR THE PHOTODECONTAMINATION OF PATHOGENS IN BLOOD | CERUS CORP (US) | 2007-02-14 | — | — | EP | disclosed |
| EP-1584622-A2 | Compounds for the photodecontamination of pathogens in blood | Cerus Corporation (US) | 2005-10-12 | — | — | EP | disclosed |
| US-20030185804-A1 | Compounds for the photodecontamination of pathogens in blood | CERUS CORPORATION (US) | 2003-10-02 | — | — | US | disclosed |
| US-6544727-B1 | Deactivating nucleic acid pathogens | CERUS CORPORATION | 2003-04-08 | — | — | US | disclosed |
| US-20020192632-A1 | Method and devices for the removal of psoralens from blood products | HEI DEREK J (US) | 2002-12-19 | — | — | US | disclosed |
| US-6469052-B2 | PSORALEN COMPOUNDS HAVE SUBSTITUTIONS ON THE 4, 4', 5', AND 8 POSITIONS WHICH PERMIT ENHANCED BINDING OF NUCLEIC ACID OF PATHOGENS | CERUS CORPORATION | 2002-10-22 | — | — | US | disclosed |
| US-20020115585-A1 | Method and devices for the removal of psoralens from blood products | HEI DEREK J (US) | 2002-08-22 | — | — | US | disclosed |
| US-20020006393-A1 | Compounds for the photodecontamination of pathogens in blood | STERITECH, INC. | 2002-01-17 | — | — | US | disclosed |
| EP-0840781-A1 | METHODS AND DEVICES FOR THE REMOVAL OF PSORALENS FROM BLOOD PRODUCTS | Cerus Corporation (US) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997021346-A1 | INACTIVATION OF NON-ENVELOPED VIRUS | CERUS CORPORATION (US) | 1997-06-19 | — | — | WO | disclosed |
| US-5625079-A | Synthesizing psoralen compounds useful as intermediates | CERUS CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5593823-A | FOR A SUFFICIENT DURATION, INTENSITY AND WAVELENGTH | CERUS CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1996040857-A1 | METHODS AND DEVICES FOR THE REMOVAL OF PSORALENS FROM BLOOD PRODUCTS | CERUS CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996039820-A1 | METHODS OF INACTIVATING LEUKOCYTES AND INHIBITING CYTOKINE PRODUCTION IN BLOOD PRODUCTS | CERUS CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5556993-A | PSORALEN COMPOUNDS FOR DEACTIVATION OF HEPATITIS AND HIVVIRUSES | STERITECH, INC. (US) | 1996-09-17 | — | — | US | disclosed |
| WO-1996014739-A1 | COMPOUNDS FOR THE PHOTODECONTAMINATION OF PATHOGENS IN BLOOD | CERUS CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |
| EP-0707476-A1 | COMPOUNDS FOR THE PHOTODECONTAMINATION OF PATHOGENS IN BLOOD | STERITECH, INC (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995000141-A1 | COMPOUNDS FOR THE PHOTODECONTAMINATION OF PATHOGENS IN BLOOD | STERITECH, INC. (US) | 1995-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030185804-A1 | Compounds for the photodecontamination of pathogens in blood | HMBS, HLA-C, HLA-B | L3MBTL1 554/4885MAPT 1645/4885HPGD 836/4885 |
| US-20020115585-A1 | Method and devices for the removal of psoralens from blood products | SERPINB10, RAD50, F2 | L3MBTL1 1637/4885MAPT 3529/4885HPGD 502/4885 |
| US-20020006393-A1 | Compounds for the photodecontamination of pathogens in blood | HMBS, HLA-C, HLA-B | L3MBTL1 554/4885MAPT 1645/4885HPGD 836/4885 |
| US-20020192632-A1 | Method and devices for the removal of psoralens from blood products | PLG, SERPINB10, RAD50 | L3MBTL1 2347/4885MAPT 3031/4885HPGD 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.