Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326392 | 0.85 | PNP (0.49) | KDM4EALDH1A1TDP1PNPPOLB | |
| SCHEMBL5428518 | 0.82 | GAA (0.40) | KDM4EALDH1A1TDP1PNPKMT2A | |
| SCHEMBL13728723 | 0.77 | GAA (0.59) | KDM4EALDH1A1PNPKMT2AMEN1 | |
| SCHEMBL3141045 | 0.76 | KMT2A (0.43) | KDM4EALDH1A1PNPKMT2AMEN1 | |
| SCHEMBL5429638 | 0.74 | CYP11B2 (0.37) | KDM4EALDH1A1TDP1PNPKMT2A | |
| SCHEMBL4379221 | 0.73 | KMT2A (0.45) | KDM4EALDH1A1TDP1PNPKMT2A | |
| SCHEMBL4090390 | 0.72 | CYP1A2 (0.46) | KDM4EALDH1A1TDP1PNPPOLB | |
| SCHEMBL4014481 | 0.70 | PNP (0.46) | KDM4EALDH1A1TDP1PNPKMT2A | |
| SCHEMBL6265339 | 0.70 | TK1 (0.62) | ALDH1A1PNPKMT2AMEN1TSHR | |
| SCHEMBL5436105 | 0.70 | ALDH1A1 (0.50) | KDM4EALDH1A1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485495-A1 | USE OF XANTHINE-DERIVATIVES AS INHIBITORS OF INDUCED BLOOD EOSINOPHILIA | Beecham Group p.l.c. (GB) | 1992-05-20 | — | — | EP | disclosed |
| WO-1991001730-A2 | USE OF XANTHINE-DERIVATIVES AS INHIBITORS OF INDUCED BLOOD EOSINOPHILIA | BEECHAM GROUP PLC (GB) | 1991-02-21 | — | — | WO | disclosed |