Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 5/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ESRRA | P11474 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875560 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HPGDMAOBMAOA | |
| SCHEMBL1377229 | 0.72 | CYP19A1 (0.62) | CYP19A1ALDH1A1HPGDPDE4BNPSR1 | |
| SCHEMBL9472016 | 0.72 | CYP19A1 (0.62) | CYP19A1ALDH1A1HPGDPDE4BNPSR1 | |
| SCHEMBL29390509 | 0.71 | CYP19A1 (0.65) | CYP19A1ALDH1A1HPGDPDE4BNPSR1 | |
| SCHEMBL4581525 | 0.71 | CYP19A1 (0.65) | CYP19A1ALDH1A1HPGDPDE4BNPSR1 | |
| SCHEMBL1377135 | 0.68 | ALDH1A1 (0.62) | CYP19A1ALDH1A1HPGDPDE4BNPSR1 | |
| SCHEMBL29688449 | 0.68 | ALDH1A1 (0.62) | CYP19A1ALDH1A1HPGDPDE4BNPSR1 | |
| SCHEMBL18170274 | 0.67 | CYP19A1 (0.61) | CYP19A1ALDH1A1HPGDPDE4BNPSR1 | |
| SCHEMBL523446 | 0.66 | ALDH1A1 (0.65) | CYP19A1ALDH1A1HPGDPDE4BNPSR1 | |
| SCHEMBL20511087 | 0.66 | CYP19A1 (0.56) | CYP19A1ALDH1A1HPGDPDE4BNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764168-B1 | HETEROATOM-FUNCTIONALIZED PORPHYRAZINES AND MULTIMETALLIC COMPLEXES AND POLYMERS DERIVED THEREFROM | HOFFMAN BARRETT L L C (US) | 2009-11-18 | — | — | EP | disclosed |
| US-5912341-A | Heteroatom-functionalized porphyrazines and multimetallic complexes and polymers derived therefrom | HOFFMAN/BARRETT, L.L.C. (US) | 1999-06-15 | — | — | US | disclosed |
| US-5675001-A | Heteroatom-functionalized porphyrazines and multimetallic complexes and polymers derived therefrom | HOFFMAN/BARRETT, L.L.C. (US) | 1997-10-07 | — | — | US | disclosed |
| EP-0764168-A1 | HETEROATOM-FUNCTIONALIZED PORPHYRAZINES AND MULTIMETALLIC COMPLEXES AND POLYMERS DERIVED THEREFROM | Hoffman/Barrett, L.L.C. (US) | 1997-03-26 | — | — | EP | disclosed |
| WO-1996028449-A1 | HETEROATOM-FUNCTIONALIZED PORPHYRAZINES AND MULTIMETALLIC COMPLEXES AND POLYMERS DERIVED THEREFROM | HOFFMAN/BARRETT, L.L.C. (US) | 1996-09-19 | — | — | WO | disclosed |