Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904690 | 0.86 | TDP1 (0.43) | TDP1POLBAPEX1L3MBTL1HDAC4 | |
| SCHEMBL4379296 | 0.82 | POLB (0.43) | TDP1POLBAPEX1L3MBTL1HDAC4 | |
| SCHEMBL14398922 | 0.79 | POLB (0.41) | TDP1POLBAPEX1L3MBTL1HDAC4 | |
| SCHEMBL4905375 | 0.77 | POLB (0.40) | TDP1POLBAPEX1L3MBTL1HDAC4 | |
| SCHEMBL28614024 | 0.77 | POLB (0.40) | TDP1POLBAPEX1L3MBTL1HDAC4 | |
| SCHEMBL6794236 | 0.77 | L3MBTL1 (0.40) | TDP1POLBAPEX1L3MBTL1HDAC4 | |
| SCHEMBL4913277 | 0.77 | POLB (0.40) | TDP1POLBAPEX1L3MBTL1HDAC4 | |
| SCHEMBL20916949 | 0.74 | BCHE (0.46) | TDP1POLBAPEX1L3MBTL1HDAC8 | |
| SCHEMBL26119733 | 0.74 | LPO (0.45) | TDP1POLBAPEX1L3MBTL1ALDH1A1 | |
| SCHEMBL161488 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371694-A | Light high-strength heat-resistant stab-resistant fiber composite material and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2025-01-28 | — | — | CN | claimed |
| CN-102153558-A | Derivative of multi-target antitumor inhibitor 2-aminopyrrole-triazine and synthesis method thereof | YANGZHOU YONGJI MEDICAL NEW TECHNOLOGY CO LTD | 2011-08-17 | — | — | CN | claimed |
| CN-1829507-A | Tyrosine kinase inhibitors | MERCK & CO INC (US) | 2006-09-06 | — | — | CN | claimed |
| EP-4504341-A1 | COMPOUNDS THAT INTERACT WITH RAS SUPERFAMILY PROTEINS FOR TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | Shy Therapeutics LLC (US) | 2025-02-12 | — | — | EP | disclosed |
| US-12215116-B2 | Arginase inhibitors and methods of use | MERCK SHARP & DOHME LLC (US) | 2025-02-04 | — | — | US | disclosed |
| CN-119371694-A | Light high-strength heat-resistant stab-resistant fiber composite material and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2025-01-28 | — | — | CN | disclosed |
| WO-2023196975-A1 | COMPOUNDS THAT INTERACT WITH RAS SUPERFAMILY PROTEINS FOR TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND FIBROTIC DISEASE | SHY THERAPEUTICS, LLC (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023107597-A2 | BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| CN-114173787-A | Dihydropyrimidine derivatives and their use in the treatment of HBV infection or HBV-induced diseases | 杨森科学爱尔兰无限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114057747-A | Dual inhibitors and uses thereof | 贝达药业股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-104292146-B | Telaprevir intermediate and preparation method thereof | 上海医药工业研究院 | 2017-04-26 | — | — | CN | disclosed |
| WO-2006020664-A2 | AMMONOLYSIS PROCESS FOR THE PREPARATION OF INTERMEDIATES FOR DPP IV INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-02-23 | — | — | WO | disclosed |
| US-20060035954-A1 | Ammonolysis process for the preparation of intermediates for DPP IV inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2006-02-16 | — | — | US | disclosed |
| US-20050271975-A1 | Films with photoresponsive wettability | WORCESTER POLYTECHNIC INSTITUTE (US) | 2005-12-08 | — | — | US | disclosed |
| US-20050256019-A1 | Enzymatic ammonolysis process for the preparation of intermediates for DPP IV inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2005-11-17 | — | — | US | disclosed |
| WO-2005108594-A1 | ENZYMATIC AMMONOLYSIS PROCESS FOR THE PREPARATION OF INTERMEDIATES FOR DPP IV INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-17 | — | — | WO | disclosed |
| EP-1581487-A2 | METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | Bristol-Myers Squibb Company (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2005059060-A1 | FILMS WITH PHOTORESPONSIVE WETTABILITY | WORCESTER POLYTECHNIC INSTITUTE (US) | 2005-06-30 | — | — | WO | disclosed |
| WO-2004052850-A2 | METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |
| US-4048191-A | Halo-substituted 1-loweralkyl-5-aroylpyrrole-2-acetic acid compounds | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035954-A1 | Ammonolysis process for the preparation of intermediates for DPP IV inhibitors | DPP4, DPP8, DPP7 | TDP1 301/4885POLB 646/4885APEX1 1862/4885 |
| US-12215116-B2 | Arginase inhibitors and methods of use | ARG1, ARG2, PRMT1 | TDP1 1482/4885POLB 2133/4885APEX1 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.