Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14377006 | 0.82 | MAPK1 (0.71) | MAPTALDH1A1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL29246344 | 0.81 | ALDH1A1 (0.78) | MAPTALDH1A1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL2892018 | 0.81 | LMNA (0.70) | MAPTALDH1A1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL3541096 | 0.80 | ALDH1A1 (0.80) | MAPTALDH1A1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL23536375 | 0.80 | KMT2A (0.59) | MAPTALDH1A1L3MBTL1MAPK1GAA | |
| SCHEMBL29932132 | 0.80 | KMT2A (0.59) | MAPTALDH1A1L3MBTL1MAPK1GAA | |
| SCHEMBL14335122 | 0.79 | MAPT (0.58) | MAPTALDH1A1L3MBTL1CYP2C19MAPK1 | |
| SCHEMBL14335232 | 0.79 | MAPT (0.54) | MAPTALDH1A1L3MBTL1MAPK1GAA | |
| SCHEMBL14334301 | 0.79 | ALDH1A1 (0.54) | MAPTALDH1A1L3MBTL1MAPK1GAA | |
| SCHEMBL14377179 | 0.79 | HTT (0.58) | MAPTALDH1A1L3MBTL1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421071-B1 | SUBSTITUTED PIPERAZINE AND DIAZEPANE DERIVAIVES AS HISTAMINE H3 RECEPTOR MODULATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-11-18 | — | — | EP | claimed |