Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.40 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.38 |
| ▸ | CNR2 | P34972 | 6/20 | 0.38 |
| ▸ | CNR1 | P21554 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4224516 | 0.88 | HDAC1 (0.39) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL4220661 | 0.86 | ALDH1A1 (0.41) | GAAHDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL4229197 | 0.85 | HDAC1 (0.41) | GAAHDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL4229364 | 0.85 | HDAC1 (0.40) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL4229423 | 0.84 | MAPT (0.42) | GAAHDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL4222628 | 0.84 | HDAC1 (0.38) | EPHX2HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL4234597 | 0.84 | MAPT (0.43) | GAAHDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL4224540 | 0.84 | EPHX2 (0.48) | EPHX2HDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL4233205 | 0.83 | CASR (0.46) | GAAHDAC1HDAC3HDAC2HDAC4 | |
| SCHEMBL4233200 | 0.82 | HDAC3 (0.41) | EPHX2HDAC1HDAC3HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2135620-A1 | OCULAR HYPOTENSIVE AGENT COMPRISING COMPOUND CAPABLE OF INHIBITING HISTONE DEACETYLASE AS ACTIVE INGREDIENT | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-23 | — | — | EP | claimed |