Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759762 | 0.90 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3950980 | 0.88 | ALDH1A1 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10575817 | 0.86 | CA12 (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10575811 | 0.86 | CA12 (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23408823 | 0.86 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7780572 | 0.83 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4537589 | 0.83 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL7001555 | 0.82 | BHMT (0.42) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL6183383 | 0.81 | MAPT (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3081779 | 0.81 | MAPT (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748805-B1 | ABSORBABLE BIOCOMPATIBLE COATINGS | BIOINTERACTIONS LTD (GB) | 2009-07-29 | — | — | EP | disclosed |
| EP-1767628-A1 | PROCESS FOR PRODUCING DIPEPTIDES OR DIPEPTIDE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-03-28 | — | — | EP | disclosed |
| EP-1748805-A1 | ABSORBABLE BIOCOMPATIBLE MATERIALS | Biointeractions Ltd. (GB) | 2007-02-07 | — | — | EP | disclosed |
| US-20060134166-A1 | Absorbable biocompatible materials | BIOINTERACTIONS LTD. (GB) | 2006-06-22 | — | — | US | disclosed |
| WO-2005115492-A1 | ABSORBABLE BIOCOMPATIBLE MATERIALS | BIOINTERACTIONS LTD (GB) | 2005-12-08 | — | — | WO | disclosed |
| EP-0581429-B1 | Process for synthesizing cyclic depsipeptides | TAKARA SHUZO CO (JP) | 1997-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060134166-A1 | Absorbable biocompatible materials | ADM2, HDGF, SLC7A1 | GABRP 2872/4885GABRD 2814/4885GABRA1 3008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.