Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGAV | P06756 | 4/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2842662 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ITGB3ITGAVITGA2BNAMPT | |
| SCHEMBL2834262 | 0.92 | TSHR (0.49) | ALDH1A1ITGB3ITGAVITGA2BNAMPT | |
| SCHEMBL2837837 | 0.92 | SIRT2 (0.42) | ALDH1A1ITGB3ITGAVITGA2BTSHR | |
| SCHEMBL2832015 | 0.91 | NAMPT (0.47) | ALDH1A1ITGB3ITGAVITGA2BNAMPT | |
| SCHEMBL2836312 | 0.89 | NAMPT (0.44) | ALDH1A1ITGB3ITGAVITGA2BNAMPT | |
| SCHEMBL2836523 | 0.88 | ADRB2 (0.44) | ALDH1A1ITGB3ITGAVITGA2BNAMPT | |
| SCHEMBL2837043 | 0.88 | ITGB3 (0.47) | ITGB3ITGAVITGA2BKCNK3HDAC1 | |
| SCHEMBL2839299 | 0.86 | ITGB3 (0.49) | ITGB3ITGAVITGA2BKCNK3HDAC1 | |
| SCHEMBL2836929 | 0.84 | NAMPT (0.46) | ALDH1A1ITGB3ITGAVITGA2BNAMPT | |
| SCHEMBL4379581 | 0.84 | NAMPT (0.46) | ALDH1A1ITGB3ITGAVITGA2BNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009061448-A9 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROTEINURIC DISEASES | THE GENERAL HOSPITAL CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |