Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351558 | 0.84 | HTR2A (0.44) | ST14SLC6A4HTR2AKCNH2CHEK2 | |
| SCHEMBL921340 | 0.84 | ST14 (0.64) | ST14SLC6A4HTR2AMAOB | |
| SCHEMBL4369759 | 0.84 | ST14 (0.64) | ST14MAOBLOXL2SOS1 | |
| SCHEMBL14667748 | 0.83 | LTA4H (0.52) | ST14SLC6A4HTR2AKCNH2CHEK2 | |
| SCHEMBL1372208 | 0.80 | ALDH1A1 (0.57) | SLC6A4HTR2AKCNH2MAOBCHEK2 | |
| SCHEMBL18210774 | 0.80 | TEAD4 (0.48) | SLC6A4HTR2AKCNH2CHEK2SOS1 | |
| SCHEMBL15832064 | 0.79 | ST14 (0.58) | ST14SLC6A4HTR2AKCNH2MAOB | |
| SCHEMBL923443 | 0.79 | ST14 (0.58) | ST14SLC6A4HTR2AKCNH2MAOB | |
| SCHEMBL52174 | 0.79 | SLC6A2 (0.51) | SLC6A4HTR2ALOXL2SLC6A2SLC6A3 | |
| SCHEMBL29817987 | 0.79 | SLC6A2 (0.51) | SLC6A4HTR2ALOXL2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |