SCHEMBL923443

SCHEMBL923443

NCc1ccc(Oc2ccc(F)c(Cl)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 3/20 0.58
SOS1 Q07889 3/20 0.58
MAOB P27338 8/20 0.46
HTR2A P28223 2/20 0.44
SLC6A4 P31645 2/20 0.44
KCNH2 Q12809 2/20 0.44
EGFR P00533 1/20 0.41
CHEK2 O96017 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32670331 0.84 SOS1 (0.55) ST14SOS1HTR2ASLC6A4KCNH2
SCHEMBL922794 0.84 ST14 (0.64) ST14MAOBHTR2ASLC6A4
SCHEMBL4369759 0.84 ST14 (0.64) ST14SOS1MAOBLOXL2
SCHEMBL4345160 0.83 SOS1 (0.65) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL14656127 0.83 SOS1 (0.54) SOS1MAOBHTR2ASLC6A4KCNH2
SCHEMBL1979103 0.80 SOS1 (0.63) SOS1MAOBHTR2ASLC6A4KCNH2
SCHEMBL14656136 0.80 SOS1 (0.51) SOS1HTR2ASLC6A4KCNH2EGFR
SCHEMBL4380034 0.79 ST14 (0.58) ST14SOS1MAOBHTR2ASLC6A4
SCHEMBL29487194 0.79 CSNK2A1 (0.50) SLC6A4LOXL2
SCHEMBL42421 0.79 CSNK2A1 (0.50) SLC6A4LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009117421-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2009-09-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ST14 708/4885SOS1 768/4885MAOB 3730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.