Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.64 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 9/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL923443 | 0.84 | ST14 (0.58) | ST14SOS1MAOBLOXL2 | |
| SCHEMBL4380034 | 0.84 | ST14 (0.58) | ST14SOS1MAOBLOXL2 | |
| SCHEMBL14662168 | 0.82 | ROCK2 (0.55) | ST14SOS1MAOBAOC3 | |
| SCHEMBL4369986 | 0.81 | ST14 (0.55) | ST14MAOBLOXL2 | |
| SCHEMBL4209153 | 0.81 | ST14 (0.85) | ST14MAOBLOXL2 | |
| SCHEMBL6159854 | 0.81 | SOS1 (0.50) | ST14SOS1MAOBSLC1A3SLC1A2 | |
| SCHEMBL5125208 | 0.81 | LTA4H (0.57) | ST14SOS1MAOBSLC1A3SLC1A2 | |
| SCHEMBL12967364 | 0.81 | SOS1 (0.50) | ST14SOS1MAOBSLC1A3SLC1A2 | |
| SCHEMBL919783 | 0.79 | LOXL2 (0.73) | ST14SOS1MAOBLOXL2 | |
| SCHEMBL506288 | 0.79 | ST14 (0.62) | ST14MAOBLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |