Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 3/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440762 | 0.93 | MTNR1A (0.41) | MTNR1AMTNR1BHCRTR1HCRTR2CCR5 | |
| SCHEMBL440763 | 0.93 | MTNR1A (0.41) | MTNR1AMTNR1BHCRTR1HCRTR2CCR5 | |
| SCHEMBL443067 | 0.78 | KMT2A (0.39) | MTNR1AMTNR1BHCRTR1HCRTR2 | |
| SCHEMBL443068 | 0.78 | KMT2A (0.39) | MTNR1AMTNR1BHCRTR1HCRTR2 | |
| SCHEMBL2596218 | 0.78 | HCRTR1 (0.41) | MTNR1AMTNR1BHCRTR1HCRTR2FABP4 | |
| SCHEMBL438005 | 0.76 | DGAT1 (0.33) | HCRTR1HCRTR2NR1H4DGAT1 | |
| SCHEMBL408844 | 0.75 | HCRTR1 (0.44) | HCRTR1HCRTR2FABP4FABP5IDH1 | |
| Trifluoroacetic Acid SCHEMBL5561399 | 0.74 | HCRTR1 (0.38) | HCRTR1HCRTR2FABP4FABP5IDH1 | |
| SCHEMBL440437 | 0.73 | DGAT1 (0.49) | HCRTR1HCRTR2DGAT1 | |
| SCHEMBL440436 | 0.73 | DGAT1 (0.49) | HCRTR1HCRTR2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | MTNR1A 1862/4885MTNR1B 1684/4885HCRTR1 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.