Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 4/20 | 0.45 |
| ▸ | PKLR | P30613 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13589015 | 0.91 | CYP3A4 (0.43) | LMNAALDH1A1MAPK1PKMPKLR | |
| SCHEMBL4382627 | 0.91 | ADAM17 (0.42) | LMNAALDH1A1TSHRMAPK1PKM | |
| SCHEMBL4382363 | 0.89 | GPBAR1 (0.47) | LMNAALDH1A1TSHRMAPK1PKM | |
| SCHEMBL4391254 | 0.89 | ADAM17 (0.44) | LMNATSHRMAPK1PKML3MBTL1 | |
| SCHEMBL8225081 | 0.88 | RORC (0.43) | ALDH1A1PKML3MBTL1ADAM17MMP1 | |
| SCHEMBL4384704 | 0.88 | L3MBTL1 (0.45) | L3MBTL1ADAM17MMP1 | |
| SCHEMBL4388230 | 0.88 | MEN1 (0.46) | LMNAALDH1A1ADAM17MMP1HTT | |
| SCHEMBL4376937 | 0.88 | ADAM17 (0.45) | LMNATSHRMAPK1L3MBTL1ADAM17 | |
| SCHEMBL4386136 | 0.88 | ADAM17 (0.43) | LMNAALDH1A1TSHRMAPK1PKM | |
| SCHEMBL4385773 | 0.88 | ADAM17 (0.43) | LMNAALDH1A1PKMPOLBADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298878-A1 | OXIME COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA L.P. | 2009-12-03 | — | — | US | disclosed |
| US-20090298878-A1 | OXIME COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA L.P. | 2009-12-03 | — | — | US | disclosed |
| US-20090298878-A1 | OXIME COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA L.P. | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298878-A1 | OXIME COMPOUNDS AND THE USE THEREOF | KCNN4, CACNA1A, KCNN3 | LMNA 3822/4885ALDH1A1 2105/4885TSHR 1691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.