SCHEMBL4380341

SCHEMBL4380341

Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C[C@H]2O)c(=S)[nH]1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 1/20 0.51
▸ FUT5 Q11128 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ P2RY2 P41231 3/20 0.49
▸ P2RY6 Q15077 2/20 0.49
▸ P2RY4 P51582 1/20 0.49
▸ P2RY1 P47900 5/20 0.49
▸ P2RX1 P51575 3/20 0.49
▸ P2RX3 P56373 3/20 0.49
▸ ENPP1 P22413 2/20 0.49
▸ P2RX4 Q99571 2/20 0.49
▸ P2RY11 Q96G91 1/20 0.49
▸ P2RX2 Q9UBL9 2/20 0.47
▸ P2RY12 Q9H244 1/20 0.47
▸ KRAS P01116 2/20 0.47
▸ RNASEL Q05823 2/20 0.46
▸ GPR17 Q13304 2/20 0.45
▸ NT5E P21589 1/20 0.45
▸ SRC P12931 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25712474 0.90 TGM2 (0.62) TGM2FUT5POLBP2RY2P2RY6
SCHEMBL1913809 0.90 TGM2 (0.62) TGM2FUT5POLBP2RY2P2RY6
SCHEMBL7065119 0.90 TGM2 (0.62) TGM2FUT5POLBP2RY2P2RY6
Deoxy Adenosinediphosphate SCHEMBL5827743 0.90 TGM2 (0.63) TGM2FUT5POLBP2RY2P2RY6
Deoxy Adenosinediphosphate SCHEMBL5827749 0.90 TGM2 (0.63) TGM2FUT5POLBP2RY2P2RY6
SCHEMBL4371131 0.86 POLB (0.67) TGM2FUT5POLBP2RY2P2RY6
SCHEMBL6740990 0.86 POLB (0.67) TGM2FUT5POLBP2RY2P2RY6
SCHEMBL596132 0.85 TGM2 (0.67) TGM2FUT5P2RY2P2RY6P2RY1
SCHEMBL18871281 0.85 TGM2 (0.67) TGM2FUT5P2RY2P2RY6P2RY1
SCHEMBL598469 0.85 TGM2 (0.67) TGM2FUT5P2RY2P2RY6P2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115380-B2 Kits and methods for generating 5′ capped RNA CELLSCRIPT, LLC (US) 2015-08-25 — — US disclosed
US-20150191760-A1 KITS AND METHODS FOR GENERATING 5' CAPPED RNA CELLSCRIPT LLC (US) 2015-07-09 — — US disclosed
US-9005930-B2 Kits and methods for generating 5′ capped RNA CELLSCRIPT, LLC (US) 2015-04-14 — — US disclosed
US-20140363876-A1 KITS AND METHODS FOR GENERATING 5' CAPPED RNA EPICENTRE TECHNOLOGIES 2014-12-11 — — US disclosed
US-8846348-B2 Kits and methods for generating 5′ capped RNA CELLSCRIPT, LLC (US) 2014-09-30 — — US disclosed
US-20140221248-A1 KITS AND METHODS FOR GENERATING 5' CAPPED RNA CELLSCRIPT, LLC (US) 2014-08-07 — — US disclosed
EP-2010659-B1 Kits and methods for generating 5' capped RNA CELLSCRIPT INC (US) 2014-06-18 — — EP disclosed
EP-2010659-A2 KITS AND METHODS FOR GENERATING 5' CAPPED RNA Epicentre Technologies (US) 2009-01-07 — — EP disclosed
US-20070281336-A1 Kits and methods for generating 5' capped RNA EPICENTRE TECHNOLOGIES (US) 2007-12-06 — — US disclosed
WO-2007120863-A2 KITS AND METHODS FOR GENERATING 5' CAPPED RNA EPICENTRE TECHNOLOGIES (US) 2007-10-25 — — WO disclosed
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