Deoxy Adenosinediphosphate

Deoxy Adenosinediphosphate

SCHEMBL5827749

Nc1nc2c(ncn2[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)CC2O)c(=O)[nH]1

nearest known ligand 0.63

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 1/20 0.63
▸ POLB P06746 1/20 0.62
▸ FUT5 Q11128 1/20 0.59
▸ P2RY2 P41231 1/20 0.58
▸ P2RY4 P51582 1/20 0.58
▸ P2RY6 Q15077 1/20 0.58
▸ NT5E P21589 1/20 0.56
▸ KRAS P01116 4/20 0.56
▸ PNP P00491 2/20 0.54
▸ POLG P54098 1/20 0.53
▸ DCPS Q96C86 1/20 0.50
▸ IMPDH2 P12268 1/20 0.49
▸ P2RX3 P56373 1/20 0.49
▸ ENPP1 P22413 1/20 0.49
▸ P2RY1 P47900 1/20 0.49
▸ P2RY12 Q9H244 1/20 0.49
▸ TAS1R3 Q7RTX0 1/20 0.48
▸ TAS1R1 Q7RTX1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxy Adenosinediphosphate SCHEMBL5827743 1.00 TGM2 (0.63) TGM2POLBFUT5P2RY2P2RY4
SCHEMBL7065119 0.99 TGM2 (0.62) TGM2POLBFUT5P2RY2P2RY4
SCHEMBL25712474 0.99 TGM2 (0.62) TGM2POLBFUT5P2RY2P2RY4
SCHEMBL1913809 0.99 TGM2 (0.62) TGM2POLBFUT5P2RY2P2RY4
SCHEMBL2922052 0.93 POLB (0.61) TGM2POLBFUT5P2RY2P2RY4
SCHEMBL20442307 0.93 POLB (0.61) TGM2POLBFUT5P2RY2P2RY4
SCHEMBL22352187 0.91 TGM2 (0.59) TGM2POLBFUT5P2RY2P2RY4
SCHEMBL5334255 0.90 FUT5 (0.58) TGM2POLBFUT5P2RY2P2RY4
SCHEMBL4380341 0.90 TGM2 (0.51) TGM2POLBFUT5P2RY2P2RY4
SCHEMBL23584319 0.90 FUT5 (0.64) TGM2POLBFUT5P2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060252115-A1 Synthesis and use of anti-reverse mRNA cap analogues DARZYNKIEWICZ EDWARD 2006-11-09 — — US disclosed
US-7074596-B2 Synthesis and use of anti-reverse mRNA cap analogues BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2006-07-11 — — US disclosed
US-20030194759-A1 Synthesis and use of anti-reverse mRBA cap analogues DARZYNKIEWICZ, EDWARD (PL) 2003-10-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252115-A1 Synthesis and use of anti-reverse mRNA cap analogues RNGTT, RNMT, CPSF6 TGM2 2476/4885POLB 228/4885FUT5 1876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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