Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.60 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.59 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.59 |
| ▸ | KRAS | P01116 | 2/20 | 0.57 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | POLG | P54098 | 1/20 | 0.54 |
| ▸ | PNP | P00491 | 1/20 | 0.53 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.51 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.49 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065119 | 1.00 | TGM2 (0.62) | TGM2POLBFUT5P2RY6P2RY2 | |
| SCHEMBL1913809 | 1.00 | TGM2 (0.62) | TGM2POLBFUT5P2RY6P2RY2 | |
| Deoxy Adenosinediphosphate SCHEMBL5827743 | 0.99 | TGM2 (0.63) | TGM2POLBFUT5P2RY6P2RY2 | |
| Deoxy Adenosinediphosphate SCHEMBL5827749 | 0.99 | TGM2 (0.63) | TGM2POLBFUT5P2RY6P2RY2 | |
| SCHEMBL20442307 | 0.92 | POLB (0.61) | TGM2POLBFUT5P2RY6P2RY2 | |
| SCHEMBL2922052 | 0.92 | POLB (0.61) | TGM2POLBFUT5P2RY6P2RY2 | |
| SCHEMBL5334255 | 0.91 | FUT5 (0.58) | TGM2POLBFUT5P2RY6P2RY2 | |
| SCHEMBL23584319 | 0.90 | FUT5 (0.64) | TGM2POLBFUT5P2RY6P2RY2 | |
| SCHEMBL4380341 | 0.90 | TGM2 (0.51) | TGM2POLBFUT5P2RY6P2RY2 | |
| SCHEMBL15833359 | 0.90 | FUT5 (0.64) | TGM2POLBFUT5P2RY6P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |