Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381249 | 0.75 | TSHR (0.38) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL16841649 | 0.70 | TSHR (0.42) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL20969054 | 0.69 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1HPGDCYP1A2 | |
| SCHEMBL43959 | 0.69 | TSHR (0.39) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL18825277 | 0.69 | GSK3A (0.61) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL2754581 | 0.69 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| Hydrochloric Acid SCHEMBL17595174 | 0.68 | TSHR (0.38) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL4671579 | 0.68 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL1824401 | 0.68 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL15693392 | 0.68 | KMT2A (0.51) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629295-B2 | Determination of a specific immunoglobulin using multiple antigens | ROCHE DIAGNOSTICS GMBH (DE) | 2009-12-08 | — | — | US | disclosed |
| US-20050074750-A1 | Determination of a specific immunoglobulin using multiple antigens | WIENHUES URSULA-HENRIKE (DE) | 2005-04-07 | — | — | US | disclosed |
| US-6613530-B1 | Epitopes; antibodies; amino acid sequences; haptens; genetic engineering; chelate compounds; biotin; carriers; use in detection of HIV or Hepatitis C-virus antibodies in liquid sample incubated in presence of solid phase and two antigens | ROCHE DIAGNOSTICS GMBH (DE) | 2003-09-02 | — | — | US | disclosed |