Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.49 |
| ▸ | GABRD | O14764 | 4/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.49 |
| ▸ | GABRE | P78334 | 4/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.49 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442158 | 0.88 | HAVCR2 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL437138 | 0.80 | NPC1 (0.56) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7502162 | 0.80 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL438308 | 0.79 | HAVCR2 (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL436434 | 0.78 | HAVCR2 (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29502985 | 0.74 | KDM4E (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL440068 | 0.73 | HAVCR2 (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL436994 | 0.73 | HAVCR2 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8803397 | 0.72 | KDM4E (0.69) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL436403 | 0.72 | POLB (0.38) | KDM4EKMT2ALMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |