Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440196 | 0.89 | NPC1 (0.52) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL439469 | 0.81 | KMT2A (0.67) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL438878 | 0.81 | KMT2A (0.71) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL437796 | 0.81 | NPC1 (0.54) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL440159 | 0.81 | MAPT (0.62) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL438132 | 0.80 | GABRP (0.49) | NPC1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL438246 | 0.76 | DPP4 (0.56) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL440489 | 0.76 | DPP4 (0.53) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL439457 | 0.75 | NPC1 (0.57) | NPC1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL439424 | 0.75 | NPC1 (0.45) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |