SCHEMBL4381868

SCHEMBL4381868

COC(F)(F)C(F)(F)C(=O)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9569891 0.80
SCHEMBL4383211 0.78 THRB (0.40)
SCHEMBL5680502 0.77
SCHEMBL1589134 0.77
SCHEMBL31582477 0.76 CES2 (0.31)
SCHEMBL11275237 0.76 F2 (0.31)
SCHEMBL1700780 0.76 DGAT1 (0.36)
SCHEMBL10340782 0.76
SCHEMBL28690309 0.74
SCHEMBL3183149 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017095732-A1 ALLYLIC TERMINALLY UNSATURATED HYDROFLUOROAMINE AND ALLYLIC TERMINALLY UNSATURATED HYDROFLUOROETHER COMPOUNDS AND METHODS OF USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-06-08 WO disclosed
EP-2044146-B1 SCORCH SAFE FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES CO (US) 2017-05-10 EP disclosed
EP-2044146-A1 SCORCH SAFE FLUOROPOLYMER COMPOSITIONS 3M Innovative Properties Company (US) 2009-04-08 EP disclosed
WO-2008014119-A1 SCORCH SAFE FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-01-31 WO disclosed
US-20080021148-A1 SCORCH SAFE FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2008-01-24 US disclosed
EP-0638112-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2002-08-07 EP disclosed
EP-0792255-B1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING & MFG (US) 2001-02-28 EP disclosed
EP-0792255-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-03 EP disclosed
WO-1996015092-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-23 WO disclosed
US-5482650-A Liquid crystal compounds having perfluoroether terminal portions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-09 US disclosed
US-4474899-A Process for preparing ester fluorinated ion exchange polymer precursor by acid treatment of ether E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-02 US disclosed
EP-0048544-B1 PREPARATION OF DIFLUOROMALONYL FLUORIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-27 EP disclosed
US-4357282-A CONTACTING A FLUORINATED METHYL OR ETHYL EHTER HAVING A METHOXYLATED CARBON ATOM WITH A LEWIS ACID CATALYST ACYLATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-02 US disclosed
US-4349650-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-14 US disclosed
EP-0048544-A1 Preparation of difluoromalonyl fluoride E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-03-31 EP disclosed
US-4316986-A Preparation of difluoromalonyl fluoride E. I. DUPONT DE NEMOURS & COMPANY (US) 1982-02-23 US disclosed
US-4292449-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-29 US disclosed
US-4275225-A Polyfluoroallyloxy compounds, their preparation and copolymers therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-23 US disclosed
US-4273729-A CARBONYL OR SULFONYL FLUORIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed
US-4273728-A NITRILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-16 US disclosed