Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | CCR1 | P32246 | 3/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.45 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560742 | 0.83 | OPRD1 (0.52) | DRD2DRD4DRD3CCR1OPRL1 | |
| SCHEMBL13788629 | 0.82 | OPRL1 (0.45) | OPRL1OPRM1OPRD1OPRK1POLB | |
| SCHEMBL10287975 | 0.81 | CCR3 (0.65) | DRD2DRD3CCR1OPRL1OPRM1 | |
| SCHEMBL8213555 | 0.80 | OPRL1 (0.67) | DRD2OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL5756820 | 0.80 | SLC6A4 (0.39) | DRD2DRD4DRD3CCR1OPRL1 | |
| SCHEMBL3852309 | 0.80 | DRD2 (0.54) | DRD2DRD4DRD3CCR1OPRL1 | |
| SCHEMBL17886590 | 0.80 | OPRL1 (0.50) | DRD2DRD4DRD3CCR1OPRL1 | |
| SCHEMBL1155345 | 0.80 | OPRM1 (0.50) | DRD2DRD4DRD3CCR1OPRL1 | |
| SCHEMBL21078101 | 0.80 | OPRL1 (0.52) | DRD2DRD4DRD3CCR1OPRL1 | |
| SCHEMBL8046465 | 0.79 | ALDH1A1 (0.67) | DRD2DRD4DRD3OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765779-B1 | NEW SUBSTITUTED PIPERIDINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | NSAB AF NEUROSEARCH SWEDEN AB (DK) | 2009-11-18 | — | — | EP | disclosed |