Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 4/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382701 | 0.90 | PKM (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL4381060 | 0.87 | TP53 (0.37) | NAMPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL4385346 | 0.85 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL4383813 | 0.85 | RORC (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4385274 | 0.83 | PKM (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL4380375 | 0.77 | CCR6 (0.45) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13589008 | 0.77 | KMT2A (0.42) | KMT2AALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL4383772 | 0.77 | ATM (0.42) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL4381306 | 0.77 | TEK (0.42) | TP53MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4384476 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298878-A1 | OXIME COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA L.P. | 2009-12-03 | — | — | US | disclosed |
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298878-A1 | OXIME COMPOUNDS AND THE USE THEREOF | KCNN4, CACNA1A, KCNN3 | NAMPT 4023/4885TP53 4415/4885ABCC9 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.