Styrene

Styrene

SCHEMBL438309

C=C[Si](OC)(OC)OC.C=Cc1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
TSHR P16473 1/20 0.58
TP53 P04637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TRPA1 O75762 3/20 0.36
HDAC8 Q9BY41 3/20 0.35
NFE2L2 Q16236 2/20 0.33
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32
TUBB6 Q9BUF5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL10912513 1.00 ALDH1A1 (0.58) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL29268852 0.87 ALDH1A1 (0.44) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL28068522 0.82 TRPA1 (0.41) ALDH1A1TSHRTP53TRPA1NFE2L2
Styrene SCHEMBL27490904 0.82 ALDH1A1 (0.52) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL10386352 0.82 ALDH1A1 (0.78) ALDH1A1TSHRTP53TDP1TRPA1
Benzene SCHEMBL28104076 0.82
Toluene SCHEMBL28147460 0.81 ACHE (0.48) ALDH1A1TSHRTP53TDP1MEN1
Styrene SCHEMBL27471538 0.80 ALDH1A1 (0.74) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL27354243 0.80 ALDH1A1 (0.74) ALDH1A1TSHRTP53TDP1TRPA1
Styrene SCHEMBL28460193 0.79 ALDH1A1 (0.58) ALDH1A1TSHRTP53TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2342272-B1 PREPARATION OF NANOSTRUCTURED MICROPOROUS COMPOSITE FOAMS UNIV NEWCASTLE (GB) 2013-09-25 EP disclosed
US-20120064243-A1 PREPARATION OF NANOSTRUCTURED MICROPOROUS COMPOSITE FOAMS NEWCASTLE UNIVERSITY (GB) 2012-03-15 US disclosed
EP-2342272-A2 PREPARATION OF NANOSTRUCTURED MICROPOROUS COMPOSITE FOAMS University Of Newcastle (GB) 2011-07-13 EP disclosed