SCHEMBL4383536

SCHEMBL4383536

O=C(O)C1C2C=CC(C2)C1C(=O)OC1CCCC1O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
POLB P06746 3/20 0.46
ALDH1A1 P00352 3/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 2/20 0.43
APEX1 P27695 1/20 0.43
FABP5 Q01469 3/20 0.38
FABP7 O15540 2/20 0.38
FABP3 P05413 2/20 0.38
HSD17B10 Q99714 1/20 0.36
KDM4E B2RXH2 1/20 0.35
TSHR P16473 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837269 0.78 FABP7 (0.51) LMNAPOLBALDH1A1SMN1; SMN2TDP1
SCHEMBL5837271 0.78 FABP7 (0.51) LMNAPOLBALDH1A1SMN1; SMN2TDP1
SCHEMBL15611584 0.76 FABP7 (0.54) LMNAPOLBALDH1A1SMN1; SMN2TDP1
SCHEMBL3288497 0.73 FABP7 (0.41) LMNAPOLBALDH1A1SMN1; SMN2TDP1
SCHEMBL12514940 0.73 LMNA (0.42) LMNAPOLBALDH1A1TDP1APEX1
SCHEMBL4665372 0.73 POLB (0.59) LMNAPOLBALDH1A1SMN1; SMN2TDP1
SCHEMBL3777075 0.73 POLB (0.59) LMNAPOLBALDH1A1SMN1; SMN2TDP1
SCHEMBL27495 0.73 POLB (0.59) LMNAPOLBALDH1A1SMN1; SMN2TDP1
SCHEMBL3787744 0.73 POLB (0.59) LMNAPOLBALDH1A1SMN1; SMN2TDP1
SCHEMBL572756 0.73 POLB (0.59) LMNAPOLBALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629424-B2 Metal-containing compositions and method of making same PRYOG, LLC (US) 2009-12-08 US claimed
US-20080015278-A1 Metal-Containing Compositions and Method of Making Same PRYOG, LLC 2008-01-17 US claimed
WO-2007070092-A2 METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME PRYOG, LLC (US) 2007-06-21 WO claimed
US-7629424-B2 Metal-containing compositions and method of making same PRYOG, LLC (US) 2009-12-08 US disclosed
US-20080015278-A1 Metal-Containing Compositions and Method of Making Same PRYOG, LLC 2008-01-17 US disclosed
WO-2007070092-A2 METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME PRYOG, LLC (US) 2007-06-21 WO disclosed