SCHEMBL5837271

SCHEMBL5837271

O=C(O)C1C2C=CC(C2)C1C(=O)OC1CCCC1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.51
FABP5 Q01469 1/20 0.51
POLB P06746 3/20 0.50
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
LMNA P02545 1/20 0.50
TDP1 Q9NUW8 2/20 0.48
APEX1 P27695 1/20 0.48
HSD17B10 Q99714 1/20 0.42
TAAR1 Q96RJ0 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837269 1.00 FABP7 (0.51) FABP7FABP5POLBALDH1A1SMN1; SMN2
SCHEMBL15611584 0.98 FABP7 (0.54) FABP7FABP5POLBALDH1A1SMN1; SMN2
SCHEMBL3286002 0.93 FABP7 (0.45) FABP7FABP5POLBALDH1A1SMN1; SMN2
SCHEMBL1614779 0.91 FABP7 (0.47) FABP7FABP5POLBALDH1A1SMN1; SMN2
SCHEMBL3288527 0.91 FABP7 (0.47) FABP7FABP5POLBALDH1A1SMN1; SMN2
SCHEMBL3288497 0.89 FABP7 (0.41) FABP7FABP5POLBALDH1A1SMN1; SMN2
SCHEMBL4383536 0.78 LMNA (0.46) FABP7FABP5POLBALDH1A1SMN1; SMN2
SCHEMBL3777075 0.77 POLB (0.59) POLBALDH1A1SMN1; SMN2LMNATDP1
SCHEMBL3787744 0.77 POLB (0.59) POLBALDH1A1SMN1; SMN2LMNATDP1
SCHEMBL4665372 0.77 POLB (0.59) POLBALDH1A1SMN1; SMN2LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7037993-B2 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2006-05-02 US disclosed
US-20050148746-A1 Norbornene-based ring-opening polymerization polymer, product of hydrogenation of norbornene-based ring-opening polymerization polymer, and processes for producing these ZEON CORPORATION (JP) 2005-07-07 US disclosed