SCHEMBL438390

SCHEMBL438390

O=C(NCn1nnc2ccccc21)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 7/20 0.62
AMY1A P0DUB6 7/20 0.62
GAA P10253 7/20 0.62
SI P14410 7/20 0.62
MGAM2 Q2M2H8 7/20 0.62
RAB9A P51151 5/20 0.62
EGLN3 Q9H6Z9 1/20 0.56
NPC1 O15118 3/20 0.56
KMT2A Q03164 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
MEN1 O00255 1/20 0.56
HSD17B10 Q99714 1/20 0.56
RPS6KA3 P51812 1/20 0.54
TP53 P04637 1/20 0.53
APAF1 O14727 1/20 0.52
POLB P06746 1/20 0.52
SLC9A1 P19634 3/20 0.51
F2 P00734 1/20 0.51
HPGD P15428 1/20 0.51
MAPT P10636 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4685940 0.89 MGAM (0.66) MGAMAMY1AGAASIMGAM2
SCHEMBL23066417 0.86 EGLN3 (0.60) MGAMAMY1AGAASIMGAM2
SCHEMBL27442553 0.86 MGAM (0.59) MGAMAMY1AGAASIMGAM2
SCHEMBL579871 0.84 RPS6KA3 (0.59) MGAMAMY1AGAASIMGAM2
SCHEMBL688425 0.82 KDM4E (0.57) MGAMAMY1AGAASIMGAM2
SCHEMBL9139443 0.82 RPS6KA3 (0.56) MGAMAMY1AGAASIMGAM2
SCHEMBL9143600 0.78 RPS6KA3 (0.59) MGAMAMY1AGAASIMGAM2
SCHEMBL13604214 0.78 RPS6KA3 (0.52) MGAMAMY1AGAASIMGAM2
SCHEMBL27417928 0.78 EGLN3 (0.66) MGAMAMY1AGAASIMGAM2
SCHEMBL21596727 0.78 GAA (0.47) MGAMAMY1AGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118515799-A Process for preparing solid support of procatalyst suitable for olefin polymerization SABIC环球技术有限责任公司 2024-08-20 CN disclosed
EP-3519457-B1 PROCESS TO PREPARE PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2024-06-12 EP disclosed
EP-3596140-B1 PROCESS FOR PREPARING A PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2024-03-20 EP disclosed
EP-3310822-B1 PROCATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING AN AMINOBENZOATE INTERNAL DONOR AND A 1,3-DIETHER INTERNAL DONOR IN A SPECIFIC RATIO SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-10-11 EP disclosed
US-11254757-B2 Process to prepare a solid support for a procatalyst suitable for polymerization of olefins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-02-22 US disclosed
EP-3083723-B1 CATALYST SYSTEM FOR POLYMERISATION OF AN OLEFIN SAUDI BASIC IND CORP (SA) 2022-01-19 EP disclosed
US-11192962-B2 Process to prepare procatalyst for polymerization of olefins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-07 US disclosed
CN-109790251-B Process for preparing procatalyst for olefin polymerization SABIC环球技术有限责任公司 2021-11-23 CN disclosed
EP-3083722-B1 CATALYST SYSTEM FOR POLYMERISATION OF AN OLEFIN SAUDI BASIC IND CORP (SA) 2021-11-10 EP disclosed
EP-3083822-B1 HETEROPHASIC PROPYLENE COPOLYMER SAUDI BASIC IND CORP (SA) 2021-09-08 EP disclosed
WO-2015091940-A1 CATALYST SYSTEM FOR POLYMERISATION OF AN OLEFIN SAUDI BASIC INDUSTRIES CORPORATION (SA) 2015-06-25 WO disclosed
WO-2015091982-A1 CATALYST SYSTEM FOR POLYMERISATION OF AN OLEFIN SAUDI BASIC INDUSTRIES CORPORATION (SA) 2015-06-25 WO disclosed
WO-2015091981-A2 CATALYST SYSTEM FOR POLYMERISATION OF AN OLEFIN SAUDI BASIC INDUSTRIES CORPORATION (SA) 2015-06-25 WO disclosed
WO-2015022298-A1 CATALYST SYSTEM FOR POLYMERISATION OF AN OLEFIN SAUDI BASIC INDUSTRIES CORPORATION (SA) 2015-02-19 WO disclosed
US-8330039-B2 Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-11 US disclosed
US-20120065196-A1 AMIDE COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-03-15 US disclosed
EP-2380208-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. du Pont de Nemours and Company (US) 2011-10-26 EP disclosed
WO-2010085664-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 WO disclosed
US-20100180947-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-22 US disclosed
WO-2008011130-A2 AMIDE COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-01-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065196-A1 AMIDE COMPOUNDS DGAT2, DGAT1, DLAT MGAM 1394/4885AMY1A 587/4885GAA 106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.