Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NMT2 | O60551 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200613 | 0.86 | KMT2A (0.45) | KMT2ANPC1RAB9AKDM4EMEN1 | |
| SCHEMBL6083583 | 0.85 | KMT2A (0.55) | KMT2ANPC1RAB9AKDM4EMEN1 | |
| SCHEMBL440043 | 0.82 | KMT2A (0.68) | KMT2ANPC1RAB9AKDM4EMEN1 | |
| SCHEMBL26167924 | 0.80 | KMT2A (0.56) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL440533 | 0.80 | KMT2A (0.65) | KMT2ANPC1RAB9AHSP90AA1KDM4E | |
| SCHEMBL438266 | 0.80 | KMT2A (0.47) | KMT2ANPC1RAB9AHSP90AA1KDM4E | |
| SCHEMBL439008 | 0.80 | NMT2 (0.60) | KMT2ANPC1RAB9AKDM4EMEN1 | |
| SCHEMBL438931 | 0.79 | HAVCR2 (0.49) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL439457 | 0.79 | NPC1 (0.57) | KMT2ANPC1RAB9AHSP90AA1KDM4E | |
| SCHEMBL436657 | 0.77 | KDM4E (0.59) | KMT2ANPC1RAB9AHSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |