Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 2/20 | 0.60 |
| ▸ | NMT1 | P30419 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437074 | 0.90 | KMT2A (0.55) | NMT2NMT1MAPTNPSR1KDM4E | |
| SCHEMBL438198 | 0.87 | MAPK1 (0.63) | NMT1MAPTNPSR1KDM4EGAA | |
| SCHEMBL538115 | 0.86 | NMT1 (0.61) | NMT2NMT1MAPTNPSR1KDM4E | |
| SCHEMBL437947 | 0.86 | KMT2A (0.53) | NMT2NMT1MAPTNPSR1KDM4E | |
| SCHEMBL538191 | 0.85 | NMT2 (0.60) | NMT2NMT1MAPTNPSR1KDM4E | |
| SCHEMBL439271 | 0.85 | MAPK1 (0.65) | NMT2NMT1MAPTNPSR1KDM4E | |
| SCHEMBL441687 | 0.85 | KMT2A (0.62) | NMT2NMT1MAPTNPSR1KDM4E | |
| SCHEMBL437781 | 0.85 | MAPT (0.61) | NMT2NMT1MAPTNPSR1KDM4E | |
| SCHEMBL22395756 | 0.85 | NMT2 (0.60) | NMT2NMT1MAPTNPSR1KDM4E | |
| SCHEMBL30900720 | 0.85 | NMT2 (0.60) | NMT2NMT1MAPTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |