Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.41 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25999187 | 0.90 | ALDH1A1 (0.47) | KMT2AALDH1A1MEN1KDM4ETSHR | |
| SCHEMBL6201539 | 0.86 | MEN1 (0.48) | KMT2AALDH1A1MEN1KDM4ETSHR | |
| SCHEMBL6084623 | 0.85 | KMT2A (0.50) | KMT2AALDH1A1MEN1KDM4ETSHR | |
| SCHEMBL30404296 | 0.85 | KMT2A (0.50) | KMT2AALDH1A1MEN1KDM4ETSHR | |
| SCHEMBL438415 | 0.80 | KMT2A (0.55) | KMT2AALDH1A1MEN1KDM4ETSHR | |
| SCHEMBL437074 | 0.80 | KMT2A (0.55) | KMT2AALDH1A1MEN1KDM4ETSHR | |
| SCHEMBL442311 | 0.79 | KDM4E (0.40) | KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL439424 | 0.79 | NPC1 (0.45) | KMT2AALDH1A1MEN1KDM4ETSHR | |
| SCHEMBL25999202 | 0.79 | DPP4 (0.51) | KMT2AALDH1A1KDM4ETSHRMAPT | |
| SCHEMBL440854 | 0.77 | AURKA (0.57) | KMT2AALDH1A1MEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |